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The mission of the C. elegans Gene Knockout Consortium is to facilitate genetic research of this important model system through the production of deletion alleles at specified gene targets.   We choose targets based on investigator requests.   At one time, our capacity dictated that we restrict requests to five per lab.   This restriction no longer holds.  Investigators are encouraged especially to register requests for functionally related groups of genes.   Please see our Frequently Asked Questions page for additional details about the operation of the consortium. Please see our guidelines for making requests.   Consortium Guidelines

Strains produced by the consortium are freely available with no restrictions to any investigator.   Consortium strains are distributed by the C. elegans Genetic Center (CGC).   In most cases, when you use the Consortium web site to request an existing allele, your request is forwarded automatically to the CGC.   However, if you indicate that an existing allele is not satisfactory for your research, (for whatever reason), you may request that we generate another allele for the same target.  

Any information generated by the Consortium is entered into the official C. elegans data repository, Wormbase.

Consortium Members
:: Oklahoma Medical Research Foundation, led by Dr. Robert Barstead
:: The University of British Columbia, led by Dr. Don Moerman
:: The Genome Sciences Centre, BC Cancer Research Centre, Vancouver

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Wednesday, July 01, 2009
As of July 1st the Oklahoma node of the C. elegans gene knockout consortium will suspend operations. If we get a favorable funding decision by the NIH/NHGRI, we will resume operations in October. The Vancouver node will continue to generate deletion strains during this interim.

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